Molecular and cellular mechanisms of lymphatic vascular maturation
Identifieur interne : 002812 ( Main/Exploration ); précédent : 002811; suivant : 002813Molecular and cellular mechanisms of lymphatic vascular maturation
Auteurs : Hong Chen ; Courtney Griffin ; Lijun Xia ; R. Sathish SrinivasanSource :
- Microvascular research [ 0026-2862 ] ; 2014.
Abstract
Lymphatic vasculature is necessary for maintaining fluid homeostasis in vertebrates. During embryogenesis lymphatic endothelial cells originate from the veins as a homogeneous population. These cells undergo a series of changes at the morphological and molecular levels to become mature lymphatic vasculature that consists of lymphatic capillaries, collecting lymphatic vessels and valves. In this article we summarize our current knowledge about these steps and highlight some black boxes that require further clarification.
Url:
DOI: 10.1016/j.mvr.2014.06.002
PubMed: 24928499
PubMed Central: 4263685
Affiliations:
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Le document en format XML
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